Search on: PROPROTEIN CONVERTASE 1 
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Descriptor English:   Proprotein Convertase 1 
Descriptor Spanish:   Proproteína Convertasa 1 
Descriptor Portuguese:   Pró-Proteína Convertase 1 
Synonyms English:   PC1 Prohormone Convertase  
Tree Number:   D08.811.277.656.300.760.640
D08.811.277.656.837.500
Definition English:   A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN. 
History Note English:   2004; for PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE, PROHORMONE CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 1991-2003; for PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE use PROPROTEIN CONVERTASE (NM) 1993-2003; for PROPROTEIN CONVERTASE SPC3 use PROPROTEIN CONVERTASE (NM) 2001-2003; for PROINSULIN CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 2002-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38169 
Unique Identifier:   D045664 

Occurrence in VHL:
 

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